Creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.
{3}, Sacrifice Glaring Spotlight: Creatures you control gain hexproof until end of turn and can't be blocked this turn.
Creatures that come under your control after Glaring Spotlight’s last ability resolves won’t have hexproof but they can’t be blocked that turn.
Creatures your opponents control don’t actually lose hexproof, although you will ignore hexproof for purposes of choosing targets of spells and abilities you control.